Tuberculosis and legionellosis vaccines and methods for their production

ABSTRACT

Vaccines and methods for their use in producing effective immune responses in mammalian hosts subsequently exposed to infection by intracellular pathogens including Legionella pneumophila wherein extracellular products of the pathogens are used as vaccines. After selecting a target intracellular pathogen, extracellular products of the selected pathogen which stimulate strong lymphocyte proliferative responses in immune hosts are then utilized as vaccines to immunize subsequent mammalian hosts to the target intracellular pathogen.



